SCH-1473759 Size:Solid 10 mg also known as INNO-206 and

also known as INNO-206 and Doxo-EMCH

136194-77-9

Smiles: CN1CCN(CC1)C(=O)C1C(C)=C(/C=C2/C3=CC(=CC=C3NC/2=O)S(=O)(=O)N(C)C2=CC(Cl)=CC=C2)NC=1C

Tolvaptan is a selective

such as kidney disease and cardiac hypertrophy

SCH-1473759 Size:Solid 10 mg also known as INNO-206 andSCH 1473759 is a potent and selective Aurora A B inhibitor with IC50 sub nanomolar. SCH 1473759 was active against a large panel of tumor cell lines from different tissue origin and genetic backgrounds. SCH 1473759 demonstrated potent mechanism based activity, and activity was shown to be enhanced in combination with taxanes and KSP inhibitors. This information may be useful for optimizing the clinical efficacy of Aurora inhibitors. Product