It inhibits PHD2 with an IC50 ~21 nM
Pifithrin-μ (PES
CAS Number: 874819-74-6
except an agonist for α4 and α6 subunit-containing ones
Temsirolimus treatment at micromolar but not nanomolar concentrations (20 μM) causes a marked decline in global protein synthesis and disassembly of polyribosomes
3α, 21-Dihydroxy-5α-pregnan-20-one 064 It inhibits PHD2 with an3,21 Dihydroxy 5 pregnan 20 one (THDOC), an endogenous neurosteroid, is a positive modulator of GABAA receptors. 3,21 Dihydroxy 5 pregnan 20 one potentiates neuronal response to low concentrations of GABA at 41 GABAA receptors in vitro. Product information CAS Number: 567 02 2 Molecular Weight: 334. 49 Formula: C21H34O3 Chemical Name: 1 [(1S,3aS,3bR,5aS,7R,9aS,9bS,11aS) 3a,3b,5a,9b tetrahydrogenio 7 hydroxy 9a,11a dimethyl hexadecahydro 1H