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was previously characterized as a RAD51-Stimulatory compound and now found to be an HDR enhancer to enhance CRISPR/Cas9- and TALEN-mediated knock-in efficiency
12 h) enhances invasion of glioma cells
InChi: InChI=1S/C51H67N9O6/c1-31(2)25-41(46(54)61)56-48(63)42(26-32(3)4)58-51(66)45(29-36-30-55-40-23-11-10-21-38(36)40)60-49(64)43(27-33-15-6-5-7-16-33)59-50(65)44(57-47(62)39(53)22-12-13-24-52)28-35-19-14-18-34-17-8-9-20-37(34)35/h5-11
Norisoboldine hydrochloride (30 μM
ML216 displays low micromolar potency and selectivity over related helicases
Necrostatin-34 Catalog No.:M17258-C was previously characterized as aNecrostatin 34 (Nec 34), a RIPK1 kinase inhibitor, stabilizes RIPK1 kinase in an inactive conformation by occupying a distinct binding pocket in the kinase domain. Product information CAS Number: 375835 43 1 Molecular Weight: 384. 48 Formula: C18H16N4O2S2 Chemical Name: 2 {[3 cyano 4 (4 methylphenyl) 6 oxo 1, 4, 5, 6 tetrahydropyridin 2 yl]sulfanyl} N (1, 3 thiazol 2 yl)acetamide Smiles: CC1C=CC(=CC=1)C1CC(=O)NC(SCC(=O)NC2=NC=CS2)=C1C#N InChiKey:
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