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Formula: C18H22F2N4O
including T315I
Chemical Name: 3-(4-hydroxyphenyl)-7-isopropoxy-4H-chromen-4-one
resulting in aneuploidy and formation of micronuclei
The discovery of the benzhydroxamate MEK inhibitors CI-1040 and PD 0325901
Torcetrapib 02895 Hydrochloride Formula: C18H22F2N4OTorcetrapib, also known as CP 529,414 was a drug being developed to treat hypercholesterolemia (elevated cholesterol levels) and prevent cardiovascular disease. Its development was halted in 2006 when phase III studies showed excessive all cause mortality in the treatment group receiving a combination of atorvastatin (Lipitor) and torcetrapib. Torcetrapib acts (as a CETP inhibitor) by inhibiting cholesterylester transfer protein (CETP), which normally
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