Porcupine-IN-1 is as potent as the clinical compound LGK974 in a cell based STF reporter gene assay
Smiles: COC1=CC(=C(C=C1)[N+]([O-])=O)S(=O)(=O)C1C=CC(Cl)=CC=1
58)59)25-42(35)54(60
Smiles: CC(C(O)=O)C1=CC(F)=C(C=C1)C1C=CC=CC=1
CAS Number: 88321-09-9
1, 2, 3, 4, 5, 6-Hexabromocyclohexane 13462 Porcupine-IN-1 is as potent as1,2,3,4,5,6 Hexabromocyclohexane (NSC7908) is a potent inhibitor of JAK2 tyrosine kinase autophosphorylation with IC50 value to be estimated in low micromolar range. Product information CAS Number: 1837 91 8 Molecular Weight: 557. 54 Formula: C6H6Br6 Chemical Name: 1,2,3,4,5,6 hexabromocyclohexane Smiles: BrC1C(Br)C(Br)C(Br)C(Br)C1Br InChiKey: QFQZKISCBJKVHI UHFFFAOYSA N InChi: InChI=1S C6H6Br6 c7 1 2(8)4(10)6(12)5(11)3(1)9 h1 6H Technical Data