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Zinc Protoporphyrin (1
TPEN (TPEDA) is a specific cell-permeable heavy metal chelator that induces apoptosis in NB4 cells via negatively regulating intracellular NO and Zn2+ signaling
is more convenient to incorporate the nitro group after deprotection lithium aluminum hydride
SAR407899 also effectively inhibits THP-1 migration with an IC50 of 2
CAS Number: 2070018-33-4
IM-250 isantherin A Zinc Protoporphyrin (1IM 250 not only reduces the duration of disease symptoms or time to healing but also prevents recurrent disease in guinea pigs. Treatment of recurrent infections reduces the frequency of recurrences and viral shedding, and, unlike nucleosidic drugs, IM 250 remains effective for a time after cessation of treatment. Hence, IM 250 has advantages over standard of care therapies and represents a promising therapeutic for chronic HSV infection, including
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