Chemical Name: (4S)-4-((2S)-1-((2S)-1-((2S)-2-((3S
Following oral administration of crystalline PF-06409577 in 0
Formula: C19H24Cl2N2
Caspase-9 cleavage
4-phenylenebis(methylene))bis(pyrimidin-2-amine)
Pimethixene maleate nic Acid Chemical Name: (4S)-4-((2S)-1-((2S)-1-((2S)-2-((3SPimethixene (Pimetixene) maleate, an antihistamine, anntimigraine agent and antiserotonergic compound, is a highly potent antagonist of a broad range of monoamine receptors, including a variety of serotonin receptors. Pimethixene maleate inhibits 5 HT2A, 5 HT2B, 5 HT2C, 5 HT1A, 5 HT1B, 5 HT6, 5 HT7, Adrenergic 1A, Dopamine D1 Receptor, Dopamine D2 Receptor, Dopamine D4. 4 Receptor, Histamine H1 Receptor, Muscarinic M1 and Muscarinic M2 with pKi of 10.